@2024 Afarand., IRAN
ISSN: 1735-7675 Kowsar Medical Journal 2011;15(4):221-225
ISSN: 1735-7675 Kowsar Medical Journal 2011;15(4):221-225
Acid-base disturbances and its related factors in patients under total intravenous anesthesia
ARTICLE INFO
Article Type
Original ResearchAuthors
Lak M. (* )Araghizadeh H. (1)
Fazel K. (1 )
(* ) Department of Anesthesiology, School of Medicine, Baqiyatallah University of Medical Sciences, Tehran, Iran
(1) Department of Anesthesiology, School of Medicine, Baqiyatallah University of Medical Sciences, Tehran, Iran
Correspondence
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marziehlak@yahoo.com
Article History
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ABSTRACT
Aims
Anesthesia duration is a risk factor of mortality and complications related to anesthesia. Metabolic acidosis is formed in patients who undergo inhalational anesthesia and has shown correlation with anesthesia duration. This study was performed in order to assess the acid-base disturbance prevalence and its related factors in total intravenous anesthesia.
Materials & Methods This descriptive study was performed on 69 patients selected by random sampling method, who referred to one of Tehran’s hospitals for elective surgery in year 2009. They were studied in 3 groups of Head and Neck surgery, extremities and abdominal surgery group. Continuous Propofol and Remifentanil infusion was used for anesthesia and acid-base status was measured. Data was analyzed using Chi square, variance analysis, repeated measurements and dependent t-test by SPSS 11.5 software.
Results Metabolic acidosis was significantly correlated with anesthesia duration. The prevalence of acidosis in Head and Neck group was greater than the two other groups. There was no significant relationship between acidosis and core body temperature changes and type and volume of injected intravenous fluids. There was no significant relationship between acidosis requiring treatment and site of surgery and anesthesia duration.
Conclusion Metabolic acidosis prevalence requiring treatment in total intravenous anesthesia is 3% and using total intravenous anesthesia including Propofol and Remifentanil in long duration anesthesia is recommended in order to reduce metabolic acidosis related complications.
Materials & Methods This descriptive study was performed on 69 patients selected by random sampling method, who referred to one of Tehran’s hospitals for elective surgery in year 2009. They were studied in 3 groups of Head and Neck surgery, extremities and abdominal surgery group. Continuous Propofol and Remifentanil infusion was used for anesthesia and acid-base status was measured. Data was analyzed using Chi square, variance analysis, repeated measurements and dependent t-test by SPSS 11.5 software.
Results Metabolic acidosis was significantly correlated with anesthesia duration. The prevalence of acidosis in Head and Neck group was greater than the two other groups. There was no significant relationship between acidosis and core body temperature changes and type and volume of injected intravenous fluids. There was no significant relationship between acidosis requiring treatment and site of surgery and anesthesia duration.
Conclusion Metabolic acidosis prevalence requiring treatment in total intravenous anesthesia is 3% and using total intravenous anesthesia including Propofol and Remifentanil in long duration anesthesia is recommended in order to reduce metabolic acidosis related complications.
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