@2024 Afarand., IRAN
ISSN: 1735-7675 Kowsar Medical Journal 2011;15(4):
ISSN: 1735-7675 Kowsar Medical Journal 2011;15(4):
Seroepidemiology of H9N2 subtype ifluenza A viruses in human population
ARTICLE INFO
Article Type
Original ResearchAuthors
Goodarzi Z. (1 )Ghorbanali Zadegan M. (2)
Pour Aliakbar M. R. (3)
Saberfar E. (*)
(*) Research Center of Virus and Vaccine, Baqiyatallah University of Medical Sciences, Tehran, Iran
(1 ) Research Center of Virus and Vaccine, Baqiyatallah University of Medical Sciences, Tehran, Iran
(2) Research Center of Molecular Biology, Baqiyatallah University of Medical Sciences, Tehran, Iran
(3) Department of Microbiology, Lahijan Branch, Islamic Azad University, Lahijan, Iran
Correspondence
Address:Phone:
Fax:
saberfar@yahoo.com
Article History
Received:Accepted:
ePublished:
ABSTRACT
Aims
Type A influenza subtype H9N2 virus is widespread among domestic poultry. These viruses were recently isolated from human beings in some countries and in several cases mortality has been reported. Since these viruses are prevalent in henhouses of our country and possibility of their transmission to the staff, this study aimed to determine the titer of the specific antibody against H9N2 influenza virus in serum sample of henhouse staff in Azerbaijan-Sharghi province.
Materials & Methods This cross-sectional study was performed on 96 henhouse employees who were selected by census sampling method in Azerbaijan-Sharghi province in year 2008. The titer of specific antibody against H9N2 influenza virus was determined by hemagglutination-inhibition test. Hemagglutination-inhibition titers Equal to or more than 1:40 were considered as positive.
Results Hemagglutination-inhibition assay in 79 cases (82%) indicated negative result and 17 cases (18%) of them indicated positive result.
Conclusion Although in this study specific antibody titer against H9N2 influenza virus is not significantly high, the results confirmed that a previous infection with H9N2 had occurred in the studied employees. However, it is recommended that for prevention of serious mutations outbreaks, the henhouse employees asked to follow and obey sanitary rules against Type A influenza subtype H9N2 infection.
Materials & Methods This cross-sectional study was performed on 96 henhouse employees who were selected by census sampling method in Azerbaijan-Sharghi province in year 2008. The titer of specific antibody against H9N2 influenza virus was determined by hemagglutination-inhibition test. Hemagglutination-inhibition titers Equal to or more than 1:40 were considered as positive.
Results Hemagglutination-inhibition assay in 79 cases (82%) indicated negative result and 17 cases (18%) of them indicated positive result.
Conclusion Although in this study specific antibody titer against H9N2 influenza virus is not significantly high, the results confirmed that a previous infection with H9N2 had occurred in the studied employees. However, it is recommended that for prevention of serious mutations outbreaks, the henhouse employees asked to follow and obey sanitary rules against Type A influenza subtype H9N2 infection.
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