@2024 Afarand., IRAN
ISSN: 1735-7675 Kowsar Medical Journal 2010;15(1):61-64
ISSN: 1735-7675 Kowsar Medical Journal 2010;15(1):61-64
Relation of 25-hydroxy vitamin D and onset of labor
ARTICLE INFO
Article Type
Original ResearchAuthors
Ahrari Kh. (* )Alizadeh Sh. A. (1 )
Abdollahi M. (2 )
(* ) Department of Midwifery, Faculty of Medical Sciences, Arak Branch, Islamic Azad University, Arak, Iran
(1 ) Department of Surgery, Arak University of Medical Sciences, Arak, Iran
(2 ) Department of Anatomy, Faculty of Medicine, Tarbiat Modarres University, Tehran, Iran
Correspondence
Article History
Received: February 13, 2008Accepted: September 10, 2008
ePublished:
ABSTRACT
Aims
The active form of vitamin D affects mineral homeostasis and bone metabolism. Stimulation effect of vitamin D in early pregnancy is effective for fetal-placental growth and development. The aim of this study is to investigate the relationship between 25-hydroxy vitamin D and initiation of labor.
Materials & Methods This study was conducted in Taleghani Hospital in Arak in 2008. 152 normal pregnant women were divided into two groups of having symptoms of labor initiation (76 cases) and without symptoms of labor initiation (76 cases). 25-hydroxy vitamin D, parathyroid hormone, calcium, phosphorus, phosphatase alkaline and magnesium of the blood were analyzed by Mann-Whitney U, linear logistic regression and student T test.
Results The mean level of 25-Hydroxy vitamin D in plasma of the labor group were more than the non-labor group (59.78±2.08 vs. 51.66±2.04 nmol/l p=0.006). The mean difference of parathyroid hormone was not significant between two groups. The mean differences of calcium, phosphorus, phosphatase alkaline and magnesium was not significant in the two groups, too.
Conclusion Considering the mean difference of 25-hydroxy vitamin D in two groups and lack of difference in the mean of parathyroid hormone, calcium, magnesium, phosphorus and phosphatase alkaline in both groups, there is the possibility of the existence 25-hydroxy vitamin D’s effect at the initiation of the labor.
Materials & Methods This study was conducted in Taleghani Hospital in Arak in 2008. 152 normal pregnant women were divided into two groups of having symptoms of labor initiation (76 cases) and without symptoms of labor initiation (76 cases). 25-hydroxy vitamin D, parathyroid hormone, calcium, phosphorus, phosphatase alkaline and magnesium of the blood were analyzed by Mann-Whitney U, linear logistic regression and student T test.
Results The mean level of 25-Hydroxy vitamin D in plasma of the labor group were more than the non-labor group (59.78±2.08 vs. 51.66±2.04 nmol/l p=0.006). The mean difference of parathyroid hormone was not significant between two groups. The mean differences of calcium, phosphorus, phosphatase alkaline and magnesium was not significant in the two groups, too.
Conclusion Considering the mean difference of 25-hydroxy vitamin D in two groups and lack of difference in the mean of parathyroid hormone, calcium, magnesium, phosphorus and phosphatase alkaline in both groups, there is the possibility of the existence 25-hydroxy vitamin D’s effect at the initiation of the labor.
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