@2024 Afarand., IRAN
ISSN: 1735-7675 Kowsar Medical Journal 2010;15(3):171-176
ISSN: 1735-7675 Kowsar Medical Journal 2010;15(3):171-176
Assessment of reasonable use of Ceftriaxone in internal and surgical wards
ARTICLE INFO
Article Type
Original ResearchAuthors
Shohrati M. (1 )Hosseini S. M. J. (* )
Rahimian S. (2 )
Parandeh Afshar P. (3 )
(* ) Molecular Biology Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran
(1 ) Chemical Injuries Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran
(2 ) Department of Clinical Pharmacology, Baqiyatallah University of Medical Sciences, Tehran, Iran
(3 ) Pharmaceutical Sciences Branch, Islamic Azad University, Tehran, Iran
Correspondence
Address:Phone:
Fax:
dr_mjhosseini@yahoo.com
Article History
Received:Accepted:
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ABSTRACT
Aims
Inappropriate use of antibiotics causes serious problems such as microorganism resistance and may lead to several side effects and even death. Drug Utilization Review studies are suitable means of drug use evaluation and revealing immethodical drug utilization trends and proposing proper solutions. This study was designed to evaluate the utilization trend of Ceftriaxone in Iran.
Materials & Methods This descriptive cross-sectional study was performed on 300 inpatients of internal and surgical wards in an educational hospital in Tehran for two six month periods in years 2008 and 2009. A protocol containing prescribing and consumption rules for ceftriaxone was prepared based on ministry of health protocol and reference books. Essential data were collected through a questionnaire designed by authors. Data was analyzed by SPSS 16.
Results Of 300 patients who entered the study, 266 cases had received the drug as surgical antibiotic prophylaxis that 32% were according to protocol and 68% were not completely according to the protocol. In 34% cases who received ceftriaxone for infection treatment, 17.4% were according to the protocol and 85.3% were not.
Conclusion There is a remarkable incoherence between current ceftriaxone use trend and the designed protocol in this study; therefore more attention should be paid to available guidelines. Establishing better surveillance methods and medical staff training programs is suggested.
Materials & Methods This descriptive cross-sectional study was performed on 300 inpatients of internal and surgical wards in an educational hospital in Tehran for two six month periods in years 2008 and 2009. A protocol containing prescribing and consumption rules for ceftriaxone was prepared based on ministry of health protocol and reference books. Essential data were collected through a questionnaire designed by authors. Data was analyzed by SPSS 16.
Results Of 300 patients who entered the study, 266 cases had received the drug as surgical antibiotic prophylaxis that 32% were according to protocol and 68% were not completely according to the protocol. In 34% cases who received ceftriaxone for infection treatment, 17.4% were according to the protocol and 85.3% were not.
Conclusion There is a remarkable incoherence between current ceftriaxone use trend and the designed protocol in this study; therefore more attention should be paid to available guidelines. Establishing better surveillance methods and medical staff training programs is suggested.
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