ARTICLE INFO

Article Type

Original Research

Authors

Ranjbar   R. (1 )
Izadi   M. (* )
Joneydi Jafari   N. (2)
Panahi   Y. (3)






(* ) Health Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran
(1 ) Molecular Biology Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran
(2) Health Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran
(3) Chemical Injuries Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran

Correspondence


Article History

Received:  
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ABSTRACT

Aims Salmonellae organisms are a large group of enteric bacteria and their infections present an important public health problem worldwide particularly in developing countries. Regretfully, Diagnosis and laboratory report of Salmonellae organisms is not performed correctly, due to a variety of reasons. This study was designed to determine the accuracy of laboratory reports of typhoid fever in Tehran during a two year period.
Methods This descriptive study was carried out on clinical samples diagnosed as Salmonella typhi received from a number of hospital laboratories in Tehran in years 2007 and 2008. Bacterial strains were diagnosed and identified by standard differential biochemical and serology tests using poly and mono specific Salmonella antisera. Results were then compared to those reported from the hospital laboratories.
Results Among 161 samples which were suspected to contain Salmonella typhi, 60 were reported as Salmonella typhi. Standard biochemical and serology test results revealed that although samples belonged to serogroup D of Salmonella, none of them had reacted with specific Salmonella antiserum; therefore, all non-typhoidal group D Salmonella strains had been misdiagnosed as Salmonella typhi.
Conclusion The precise laboratory identification of Salmonella typhi should be emphasized, because laboratory reports with misdiagnosed Salmonella typhi may prevent physicians from taking proper supportive and curative measures and impair the treatment process.


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