@2024 Afarand., IRAN
ISSN: 2252-0805 The Horizon of Medical Sciences 2018;24(1):7-11
ISSN: 2252-0805 The Horizon of Medical Sciences 2018;24(1):7-11
Effect of One Period of Resistance Training on Some Fibrinolytic Factors of Active Young Men
ARTICLE INFO
Article Type
Original ResearchAuthors
Khosravi N. (*)Kordi N. (1)
(*) Exercise Physiology Department, Physical Education & Sport Sciences Faculty, Alzahra University, Tehran, Iran
(1) Exercise Physiology Department, Physical Education & Sport Sciences Faculty, Alzahra University, Tehran, Iran
Correspondence
Article History
Received: February 13, 2017Accepted: November 8, 2017
ePublished: January 11, 2018
ABSTRACT
Aims
Fluctuation in the homeostasis system is one of the main causes of heart attacks. Physical activity plays an important role in automatic control of the cardiovascular system. This study aimed at investigating the effect of one period of resistance training on some fibrinolytic factors in active young men.
Materials & Methods In this semi-experimental study, 30 young male athletes belonging to a gym in Qom, Iran were selected through convenience sampling method in 2016; they were randomly assigned to single-joint resistance training, multi-joint resistance training, and control groups (N=10). The training protocol was implemented 3 sessions per week for 8 weeks. In order to evaluate the serum levels of fibrinogen, PT (Prothrombin Time), and PTT (Partial Thromboplastin Time), 6cc blood sample was collected from participants before training and after the last training session. The data were analyzed by SPSS 20, using factor analysis of variance (2×3), Bonferroni's post hoc test, and paired t-test.
Findings Regardless of the type of protocol, a resistance training period reduced fibrinogen (p=0.0001) and increased prothrombin time (p=0.047), but it did not significantly change partial thromboplastin time (p=0.111).
Conclusion Resistance training reduces the fibrinogen amount and increases PT in active young men, but it does not change PTT.
Materials & Methods In this semi-experimental study, 30 young male athletes belonging to a gym in Qom, Iran were selected through convenience sampling method in 2016; they were randomly assigned to single-joint resistance training, multi-joint resistance training, and control groups (N=10). The training protocol was implemented 3 sessions per week for 8 weeks. In order to evaluate the serum levels of fibrinogen, PT (Prothrombin Time), and PTT (Partial Thromboplastin Time), 6cc blood sample was collected from participants before training and after the last training session. The data were analyzed by SPSS 20, using factor analysis of variance (2×3), Bonferroni's post hoc test, and paired t-test.
Findings Regardless of the type of protocol, a resistance training period reduced fibrinogen (p=0.0001) and increased prothrombin time (p=0.047), but it did not significantly change partial thromboplastin time (p=0.111).
Conclusion Resistance training reduces the fibrinogen amount and increases PT in active young men, but it does not change PTT.
CITATION LINKS
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[7]Kupchak BR, Creighton BC, Aristizabal JC, Dunn Lewis C, Volk BM, Ballard KD, et al. Beneficial effects of habitual resistance exercise training on coagulation and fibrinolytic responses. Thromb Res. 2013;131(6):e227-34.
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[9]Mirsaeedi M, Mahdiraji HA, Khameshlu B, Mazidi A, Akhundi A. Comparison the effect of aerobic and resistance exercises in Sari olderly sedentary men on coagulation and fibrinolytic factors. Annal Biological Res 2012;3(5):2083-86.
[10]Kumar A, Kar S, Fay WP. Thrombosis, physical activity, and acute coronary syndromes. J Appl Physiol. 2011;111(2):599-605.
[11]El Sayed MS, El Sayed AZ, Ahmadizad S. Exercise and training effects on blood haemostasis in health and disease: An update. Sports Med. 2004;34(3):181-200.
[12]Peat EE, Dawson M, McKenzie A, Hillis WS. Thw effect of acute-dynamic exercise on haemostasis in first class scottish football referees. Br J Sports Med. 2010;44(8):573-8.
[13]Habibi M, Torkaman G, Goosheh B, Hedayati M. The effect of combined resistance-aerobic and aerobic training on the coagulative factors of young healthy men. Physiol Pharmacol. 2009;13(1):98-107. [Persian]
[14]Ahmadizad S, EL Sayed MS. The acute effects of resistance exercise on the main determinants of blood rheology. J Sports Sci. 2005;23(3):243-9.
[15]Fathei M, Mir E. The effect of 12 resistance training sessions on some coagulation and fibrinolytic factors in non-active men. J Pract Stud Biosci Sport. 2015;3(5):56-66. [Persian]
[16]Kordi MR, Ahmadi zad S, Dabaq Nikokheslat S, Gaeeni AA, Ravasi AA, Ebrahimi H, et al. The effects of 12 weeks of resistance trainingon responses to a single session and resting levels ofhemorheological and coagulation variables of young men. Res Sport Sci. 2009;27(3):105-22. [Persian]
[17]Hilberg T, Prasa D, Sturzebecher J, Glaser D, Gabriel HH. Thrombin potential and thrombin generation after exhaustive exercise. Int J Sports Med. 2002;23(7):500-4.
[18]Li N, He S, Blombäck M, Hjemdahl P. Platelet activity, coagulation and fibrinolysis during exercise in healthy males: Effects of thrombin inhibition by argatroban and enoxaparin. Arterioscler Thromb Vasc Biol. 2007;27(2):407-13.
[19]Amini A, Kordi MR, Gaini AA, Ahmadi A, Veysi K. Effect of resistance exercise on coagulation an fibrinolytic factors in inactive aged men. Horizon Med Sci. 2012;18(3):103-8. [Persian]
[20]Menzel K, Hilberg T. Coagulation and fibrinolysis are in balance after moderate exercise in middle-aged participant. Clin Appl Thromb Hemost. 2009;15(3):348-55.
[21]Barani f, Afzalpour ME, Ilbeigi S, Kazemi T, Mohammadi Fard M. The effect of resistance and combined exercise on serum C-Reactive Protein (hs-CRP) and body composition characteristics in patients with nonalcoholic fatty liver disease. J Zabol Univ Med Sci Health Serv. 2016;7(4):1-14. [Persian]
[22]Gharari Arefi R, Chubineh S, Kordi MR. The effect of a high-intensity interval training on some of factors affecting erythrocyte sedimentation rate in sedentary young men. J Pract Stud Biosci Sport. 2016;3(6):74-83. [Persian]
[23]Jung F, Pindur G, Kiesewetter H. Plasma viscosity dependence on proteins and lipoproteins. Clin Hemorheol Microcirc. 1992;12(4):557-71.
[24]Piccono G, Fazio F, Giudice E, Caola G. Exercise-induced change in clotting times and fibrinolytic activity during official 1600 and 2000 meters trot races in standard hores. Acta Vet Brno. 2005;74:509-14.
[25]Amouzad Mahdirejei H, Aghababaeian A, Mirsaiedii M, Fadaei Reyhan Abadei S, Abbaspour Seyedii A. Effect of 8 weeks of resistance training on hemostasis indeces and lipid profile in adult men. J Gorgan Univ Med Sci. 2014:16(2);21-8. [Persian]
[2]Ahmadizad S, El Sayed MS. The effects of graded resistance exercise on platelet aggregation and activation. Med Sci Sports Exerc. 2003;35(6):1026-32.
[3]Senen K, Topal E, Kilinc E, ten Cate H, Tek I, Karakoc Y, et al. Plasma viscosity and mean platelet volume in patients undergoing coronary angiography. Clin Hemorheol Microcirc. 2010;44(1):35-41.
[4]Alzahrani SH, Ajjan RA. Coagulation and fibrinolysis in diabetes. Diab Vasc Dis Res. 2010;7(4):260-73.
[5]Ghanbari AR, Tayebi SM. The effect of a single session eccentric resistance exercise on some blood coagulation factors of inactive male student. Sci J Iran Blood Transfus Organ. 2011;8(3):195-206. [Persian]
[6]Smith J. Effects of strenuous exercise on haemostasis. Br J Sports Med. 2003;37(5):433-5.
[7]Kupchak BR, Creighton BC, Aristizabal JC, Dunn Lewis C, Volk BM, Ballard KD, et al. Beneficial effects of habitual resistance exercise training on coagulation and fibrinolytic responses. Thromb Res. 2013;131(6):e227-34.
[8]Van Den Burg PJ, Hospers JE, Mosterd WL, Bouma BN, Huisveld IA. Aging physical conditioning and exercise-induced changes in hemostatic factors and reaction products. J Appl Physiol. 2000;8(5):1558-64.
[9]Mirsaeedi M, Mahdiraji HA, Khameshlu B, Mazidi A, Akhundi A. Comparison the effect of aerobic and resistance exercises in Sari olderly sedentary men on coagulation and fibrinolytic factors. Annal Biological Res 2012;3(5):2083-86.
[10]Kumar A, Kar S, Fay WP. Thrombosis, physical activity, and acute coronary syndromes. J Appl Physiol. 2011;111(2):599-605.
[11]El Sayed MS, El Sayed AZ, Ahmadizad S. Exercise and training effects on blood haemostasis in health and disease: An update. Sports Med. 2004;34(3):181-200.
[12]Peat EE, Dawson M, McKenzie A, Hillis WS. Thw effect of acute-dynamic exercise on haemostasis in first class scottish football referees. Br J Sports Med. 2010;44(8):573-8.
[13]Habibi M, Torkaman G, Goosheh B, Hedayati M. The effect of combined resistance-aerobic and aerobic training on the coagulative factors of young healthy men. Physiol Pharmacol. 2009;13(1):98-107. [Persian]
[14]Ahmadizad S, EL Sayed MS. The acute effects of resistance exercise on the main determinants of blood rheology. J Sports Sci. 2005;23(3):243-9.
[15]Fathei M, Mir E. The effect of 12 resistance training sessions on some coagulation and fibrinolytic factors in non-active men. J Pract Stud Biosci Sport. 2015;3(5):56-66. [Persian]
[16]Kordi MR, Ahmadi zad S, Dabaq Nikokheslat S, Gaeeni AA, Ravasi AA, Ebrahimi H, et al. The effects of 12 weeks of resistance trainingon responses to a single session and resting levels ofhemorheological and coagulation variables of young men. Res Sport Sci. 2009;27(3):105-22. [Persian]
[17]Hilberg T, Prasa D, Sturzebecher J, Glaser D, Gabriel HH. Thrombin potential and thrombin generation after exhaustive exercise. Int J Sports Med. 2002;23(7):500-4.
[18]Li N, He S, Blombäck M, Hjemdahl P. Platelet activity, coagulation and fibrinolysis during exercise in healthy males: Effects of thrombin inhibition by argatroban and enoxaparin. Arterioscler Thromb Vasc Biol. 2007;27(2):407-13.
[19]Amini A, Kordi MR, Gaini AA, Ahmadi A, Veysi K. Effect of resistance exercise on coagulation an fibrinolytic factors in inactive aged men. Horizon Med Sci. 2012;18(3):103-8. [Persian]
[20]Menzel K, Hilberg T. Coagulation and fibrinolysis are in balance after moderate exercise in middle-aged participant. Clin Appl Thromb Hemost. 2009;15(3):348-55.
[21]Barani f, Afzalpour ME, Ilbeigi S, Kazemi T, Mohammadi Fard M. The effect of resistance and combined exercise on serum C-Reactive Protein (hs-CRP) and body composition characteristics in patients with nonalcoholic fatty liver disease. J Zabol Univ Med Sci Health Serv. 2016;7(4):1-14. [Persian]
[22]Gharari Arefi R, Chubineh S, Kordi MR. The effect of a high-intensity interval training on some of factors affecting erythrocyte sedimentation rate in sedentary young men. J Pract Stud Biosci Sport. 2016;3(6):74-83. [Persian]
[23]Jung F, Pindur G, Kiesewetter H. Plasma viscosity dependence on proteins and lipoproteins. Clin Hemorheol Microcirc. 1992;12(4):557-71.
[24]Piccono G, Fazio F, Giudice E, Caola G. Exercise-induced change in clotting times and fibrinolytic activity during official 1600 and 2000 meters trot races in standard hores. Acta Vet Brno. 2005;74:509-14.
[25]Amouzad Mahdirejei H, Aghababaeian A, Mirsaiedii M, Fadaei Reyhan Abadei S, Abbaspour Seyedii A. Effect of 8 weeks of resistance training on hemostasis indeces and lipid profile in adult men. J Gorgan Univ Med Sci. 2014:16(2);21-8. [Persian]