@2024 Afarand., IRAN

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ISSN: 2251-8215    Sarem Journal of Reproductive Medicine 2018;2(2):

Information & Methods Pregnancy is rare in most women with Cushing's syndrome (CS) due to the lack of ‎ovulation. A 36-year-old woman, who had experienced cesarean section in her ‎first pregnancy and her second pregnancy had occurred despite the Intrauterine ‎Device (IUD), was referred to the hospital. The results of routine pregnancy tests ‎and screening tests indicated normal general conditions. At the 12th week of ‎pregnancy, the first manifestation of blood pressure was observed. During the ‎pregnancy, the patient was constantly monitored and, finally, at the 34th week, ‎she underwent cesarean section due to the severity of symptoms, cesarean section ‎history, and delayed fetal infarction. A boy was born, weighing 1700 grams and ‎was hospitalized in the NICU ward. Regarding the lack of control of blood pressure ‎after pregnancy, an abdominal MRI was asked for the patient to examine the renal ‎artery; a 3cm mass was reported in her right adrenal, and a diagnosis of Cushing's ‎syndrome was presented to her. The right laparoscopic adrenalectomy was ‎conducted for the patient and gradually the Corton intake was stopped. After the ‎recent procedures, all of the patient’s symptoms, including hypertension, edema, ‎proteinuria, hyperglycemia, and hyperlipidemia were resolved. Proximal muscles ‎pain and weakness remained about 1 year after her laparoscopic adrenalectomy, ‎and they were improved by physiotherapy.‎
Conclusion Secondary hypertension can occur due to Renovascular hypertension, ‎pheochromocytoma, and Cushing’s syndrome. Although Cushing's syndrome is ‎rare in pregnancy, these cases can be accompanied by hypertension, ‎preeclampsia, preterm labor, and fetal loss. Therefore, a more complete ‎assessment and attention to important symptoms such as blood pressure is ‎necessary to prevent the complications.‎