ARTICLE INFO

Article Type

Original Research

Authors

Saremi   A.T. (1)
MehdiZadeh Shahi   A. (*)
Pooladi ‎   A. (1)
Shami   M. (2)
Safavi   M. (2)






(*) Sarem Women’s Hospital, Tehran, Iran
(1) ‎“Sarem Fertility & Infertility Research Center (SAFIR)” and “Sarem Cell Research Center (SCRC)” ‎, Sarem Women’s Hospital, Tehran, Iran
(1) ‎“Sarem Fertility & Infertility Research Center (SAFIR)” and “Sarem Cell Research Center (SCRC)” ‎, Sarem Women’s Hospital, Tehran, Iran
(2) Sarem Women’s Hospital, Tehran, Iran

Correspondence

Article History

Received:   April  24, 2017
Accepted:   October 16, 2017
ePublished:   November 15, 2018

ABSTRACT

Aims Ovulation induction is one of the main steps in assisted reproductive technology ‎‎(ART). Ovarian hyperstimulation syndrome (OHSS) is a serious complication of ‎ART. The patients with polycystic ovary (PCO) are at higher risk for OHSS when ‎they are subjected to such techniques. The objective of this study was to ‎investigate the pregnancy outcomes of mild and moderate OHSS in PCO and non-‎PCO patients.‎
Materials & Methods This retrospective cross-sectional study was carried out on 321 OHSS patients ‎candidate for IVF/ICSI based on their medical records in Sarem Women’s Hospital ‎‎(Tehran, Iran) in a period of two years. The general characteristics of the patients ‎and the parameters related to pregnancy were compared between the group of PCO ‎and non-PCO patients. Data were analyzed by Fisher exact test and T-test using ‎SPSS 13 software.‎
Findings A significant difference was found in hospitalization periods between PCO and ‎non-PCO groups (p=0.002). The PCO group showed higher level of OHSS severity ‎compared to the non-PCO group (p=0.0001). The number of transferred embryo ‎had significant difference between PCO and non-PCO groups (p=0.015). There was ‎no significant difference in clinical pregnancy success rate between PCO (11.8%) ‎and non-PCO (14.2%) patients (p=0.602).‎
Conclusion In OHSS patients, the overall pregnancy success rate is lower than normal. The ‎PCO background is not a determining factor for the pregnancy success rate in the ‎patients with OHSS. A similar pregnancy success rate can be achieved by longer ‎duration of treatment for OHSS and more number of transmitted embryos in ‎individuals with PCO‏.‏

Keywords: Ovarian Hyperstimulation Syndrome (OHSS) ‎, Polycystic Ovary Syndrome (PCO) ‎, Pregnancy Outcome ‎,

CITATION LINKS

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