@2024 Afarand., IRAN
ISSN: 2252-0805 The Horizon of Medical Sciences 2016;22(2):165-170
ISSN: 2252-0805 The Horizon of Medical Sciences 2016;22(2):165-170
Comparison of Brain CT Scan and without Contrast MRI Findings of Epileptic Children
ARTICLE INFO
Article Type
Descriptive & Survey StudyAuthors
Fallah R. (1)Falahatian Mehrjardi H. (2)
Nafisi Moghadam R. (*)
Sepehri M. (3)
(*) Radiologist Department, Medicine Faculty, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
(1) “Growth Disorders of Children Research Center” and “Pediatrics Department, Medicine Faculty”, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
(2) Pediatrics Department, Ali-ebn-Abitaleb School of Medicine, Yazd Branch, Islamic Azad University, Yazd, Iran
(3) Medicine Department, Medicine Faculty, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Correspondence
Address: Radiology Department, Shahid Sadoughi Hospital, Ave-Sina Boulevard, Shahid Ghandi Boulevard, Safaeieh,Yazd, IranPhone: +983538224000
Fax: +983538224100
nafisi.moghadam@gmail.com
Article History
Received: July 17, 2015Accepted: January 2, 2016
ePublished: March 5, 2016
ABSTRACT
Aims
Epilepsy is one of the most common children diseases, and MRI is a method to understand its etiology. Since there was no MRI in many medical centers, the aim of this study was to compare the findings of CT scan and MRI without contrast in epileptic children.
Materials & Methods In this descriptive-analytic study, 1-month to 14-year old epileptic children (n=160) referred to Pediatric Neurology Clinic of Yazd Shahid Sadoughi Medical University were studied in September 2012. Data was recorded in a questionnaire via interviews with the parents, biography, physical exams, and investigating the findings of CT scan and MRI. Data was analyzed in SPSS 15 software using Chi-square test.
Findings There were normal and abnormal CT scans in 121 (75.6%) and 39 (24.4%) children, respectively. There were normal and abnormal MRI findings in 84 (52.5%) and 76 (47.5%) children, respectively. The results of CT scan and MRI were consistent in 119 (73.4%) children (p=0.001). There were more prevalent abnormal CT scans in less than 6 months children, developmental delayed children, abnormal physical exam, and epileptic abnormal electroencephalography. There were more prevalent abnormal MRI cases in 2-14 years children, developmental delayed children, abnormal physical exam, focal seizure, and non-specific abnormal electroencephalography.
Conclusion To investigate 2-14 years old epileptic children, focal seizure, and non-specific abnormal electroencephalography, MRI is preferable than CT scan. The latter is useful in less than 6 months children, developmental delayed children, abnormal physical exam, and epileptic abnormal electroencephalography.
Materials & Methods In this descriptive-analytic study, 1-month to 14-year old epileptic children (n=160) referred to Pediatric Neurology Clinic of Yazd Shahid Sadoughi Medical University were studied in September 2012. Data was recorded in a questionnaire via interviews with the parents, biography, physical exams, and investigating the findings of CT scan and MRI. Data was analyzed in SPSS 15 software using Chi-square test.
Findings There were normal and abnormal CT scans in 121 (75.6%) and 39 (24.4%) children, respectively. There were normal and abnormal MRI findings in 84 (52.5%) and 76 (47.5%) children, respectively. The results of CT scan and MRI were consistent in 119 (73.4%) children (p=0.001). There were more prevalent abnormal CT scans in less than 6 months children, developmental delayed children, abnormal physical exam, and epileptic abnormal electroencephalography. There were more prevalent abnormal MRI cases in 2-14 years children, developmental delayed children, abnormal physical exam, focal seizure, and non-specific abnormal electroencephalography.
Conclusion To investigate 2-14 years old epileptic children, focal seizure, and non-specific abnormal electroencephalography, MRI is preferable than CT scan. The latter is useful in less than 6 months children, developmental delayed children, abnormal physical exam, and epileptic abnormal electroencephalography.
CITATION LINKS
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[2]Camfield P, Camfield C. Incidence, prevalence and aetiology of seizures and epilepsy in children. Epileptic Disord. 2015;17(2):117-23.
[3]Gaillard WD, Chiron C, Cross JH, Harvey AS, Kuzniecky R, Hertz-Pannier L, et al. ILAE, Committee for Neuroimaging, Subcommittee for Pediatric. Guidelines for imaging infants and children with recent-onset epilepsy. Epilepsia. 2009;50(9):2147-53.
[4]Hirtz D, Ashwal S, Berg A, Bettis D, Camfield C, Camfield P, et al. Practice parameter: Evaluating a first nonfebrile seizure in children: Report of the quality standards subcommittee of the American Academy of Neurology, the Child Neurology Society, and the American Epilepsy Society. Neurol. 2000;55(5):616-23.
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[6]Wilden JA, Cohen-Gadol AA. Evaluation of first nonfebrile seizures. Am Fam Physician. 2012;86(4):334-40.
[7]Ben Ameur S, Aloulou H, Sfaihi L, Yaich S, Mnif Z, Kamoun T, et al. [Cerebral imaging in epileptic children: Study of 140 cases]. Tunis Med. 2014;92(1):24-8. [French]
[8]Fallah R, Abedi M. The evaluation of children brain CT scan results and it's relationship with requesting clinical complaints. Q Horizon Med Sci. 2008;14(1):27-32. [Persian]
[9]Patel NH, Jain AR, Iyer VK, Shah AG, Jain DA, Shah AA. Clinico - diagnostic and therapeutic relevance of computed tomography scan of brain in children with partial seizures. Ann Indian Acad Neurol. 2013;16(3):352-6.
[10]Strobel AM, Gill VS, Witting MD, Teshome G. Emergent diagnostic testing for pediatric nonfebrile seizures. Am J Emerg Med. 2015; 33(9):1261-4.
[11]Al-Rumayyan AR, Abolfotouh MA. Prevalence and prediction of abnormal CT scan in pediatric patients presenting with a first seizure. Neurosci. 2012;17(4):352-6.
[12]Bautovich T, Numa A. Role of head computed tomography in the evaluation of children admitted to the paediatric intensive care unit with new-onset seizure. Emerg Med Australas. 2012;24(3):313-20.
[13]Fallah R, Nafisi Moghadam R, Fallah Tafti M, Salmani Nodoushan M. Results of noncontrast brain computed tomography scans of 1-18 year old epileptic children. Iran J Child Neurol. 2012;6(3):33-8.
[14]Hsieh DT, Chang T, Tsuchida TN, Vezina LG, Vanderver A, Siedel J, Brown K, et al. New-onset afebrile seizures in infants: role of neuroimaging. Neurol. 2010;74(2):150-6.
[15]Khodapanahandeh F, Hadizadeh H. Neuroimaging in children with first afebrile seizures: to order or not to order?. Arch Iran Med. 2006;9(2):156-8.
[16]Amirsalari S, Saburi A, Hadi R, Torkaman M, Beiraghdar F, Afsharpayman S, et al. Magnetic resonance imaging findings in epileptic children and its relation to clinical and demographic findings. Acta Med Iran. 2012;50(1):37-42.
[17]Tews W, Weise S, Syrbe S, Hirsch W, Viehweger A, Merkenschlager A, et al. Is there a predictive value of EEG and MRI after a first afebrile seizure in children?. Klin Padiatr. 2015;227(2):84-8.
[18]Mohamed Y, Alias NN, Shuaib IL, Tharakan J, Abdullah J, Munawir AH, et al. Referral of epileptic patients in North East Coast of West Malaysia an area with poor MRI coverage: an analysis. Southeast Asian J Trop Med Public Health. 2006;37(6):1199-208.
[19]Byars AW, deGrauw TJ, Johnson CS, Fastenau PS, Perkins SM, Egelhoff JC, et al. The Association of MRI findings and neuropsychological functioning after the first recognized seizure. Epilepsia. 2007;48(6):1067-74.
[20]Dehghani Firuzabadi M, Mohammadifarrd M, Sharifzadeh G, Mohammadifard M. MRI findings and clinical symptoms of patients with epilepsy referring to Valli-e-asr Hospital between 2009 and 2010. J Birjand Univ Med Sci. 2013;19(4):422-9. [Persian]
[21]Grévent D, Calmon R, Brunelle F, Boddaert N. [Brain imaging in seizures]. Rev Prat. 2012;62(10):1391-4. [French]
[22]Sharieff GQ, Hendry PL. Afebrile pediatric seizures. Emerg Med Clin North Am. 2011;29(1):95-108.
[23]Hashemi AH, Homam M, Naghib S. Unenhanced brain CT findings in afebrile patients over five years age with first episode of seizure. Iran J Radiol. 2008;5(Suppl 1):32-3. [Persian]
[24]Nasehi MM, Shamsabadi F, Ghofrani M. Paraclinical findings and treatment response of children with refractory epilepsy in Mofid Children's Hospital in 2007-2008. J Mazandaran Univ Med Sci. 2009;20(75):24-9. [Persian]
[25]Sue H, Nakayama K. [Clinical examination on localization-related epilepsies with elementary visual seizures--clinical, electroencephalographic and imaging diagnostic studies]. Seishin Shinkeigaku Zasshi. 1997;99(9):688-705. [Japanese]
[26]Sanmaneechai O, Danchaivijitr N, Likasitwattanakul S. Predictors of abnormal neuroimaging of the brain in children with epilepsy aged 1 month to 2 years: useful clues in a resource-limited setting. J Child Neurol. 2015;30(11):1532-6.
[2]Camfield P, Camfield C. Incidence, prevalence and aetiology of seizures and epilepsy in children. Epileptic Disord. 2015;17(2):117-23.
[3]Gaillard WD, Chiron C, Cross JH, Harvey AS, Kuzniecky R, Hertz-Pannier L, et al. ILAE, Committee for Neuroimaging, Subcommittee for Pediatric. Guidelines for imaging infants and children with recent-onset epilepsy. Epilepsia. 2009;50(9):2147-53.
[4]Hirtz D, Ashwal S, Berg A, Bettis D, Camfield C, Camfield P, et al. Practice parameter: Evaluating a first nonfebrile seizure in children: Report of the quality standards subcommittee of the American Academy of Neurology, the Child Neurology Society, and the American Epilepsy Society. Neurol. 2000;55(5):616-23.
[5]Adamsbaum C, Rolland Y, Husson B. [Pediatric neuroimaging emergencies]. J Neuroradiol. 2004;31(4):272-80. [French]
[6]Wilden JA, Cohen-Gadol AA. Evaluation of first nonfebrile seizures. Am Fam Physician. 2012;86(4):334-40.
[7]Ben Ameur S, Aloulou H, Sfaihi L, Yaich S, Mnif Z, Kamoun T, et al. [Cerebral imaging in epileptic children: Study of 140 cases]. Tunis Med. 2014;92(1):24-8. [French]
[8]Fallah R, Abedi M. The evaluation of children brain CT scan results and it's relationship with requesting clinical complaints. Q Horizon Med Sci. 2008;14(1):27-32. [Persian]
[9]Patel NH, Jain AR, Iyer VK, Shah AG, Jain DA, Shah AA. Clinico - diagnostic and therapeutic relevance of computed tomography scan of brain in children with partial seizures. Ann Indian Acad Neurol. 2013;16(3):352-6.
[10]Strobel AM, Gill VS, Witting MD, Teshome G. Emergent diagnostic testing for pediatric nonfebrile seizures. Am J Emerg Med. 2015; 33(9):1261-4.
[11]Al-Rumayyan AR, Abolfotouh MA. Prevalence and prediction of abnormal CT scan in pediatric patients presenting with a first seizure. Neurosci. 2012;17(4):352-6.
[12]Bautovich T, Numa A. Role of head computed tomography in the evaluation of children admitted to the paediatric intensive care unit with new-onset seizure. Emerg Med Australas. 2012;24(3):313-20.
[13]Fallah R, Nafisi Moghadam R, Fallah Tafti M, Salmani Nodoushan M. Results of noncontrast brain computed tomography scans of 1-18 year old epileptic children. Iran J Child Neurol. 2012;6(3):33-8.
[14]Hsieh DT, Chang T, Tsuchida TN, Vezina LG, Vanderver A, Siedel J, Brown K, et al. New-onset afebrile seizures in infants: role of neuroimaging. Neurol. 2010;74(2):150-6.
[15]Khodapanahandeh F, Hadizadeh H. Neuroimaging in children with first afebrile seizures: to order or not to order?. Arch Iran Med. 2006;9(2):156-8.
[16]Amirsalari S, Saburi A, Hadi R, Torkaman M, Beiraghdar F, Afsharpayman S, et al. Magnetic resonance imaging findings in epileptic children and its relation to clinical and demographic findings. Acta Med Iran. 2012;50(1):37-42.
[17]Tews W, Weise S, Syrbe S, Hirsch W, Viehweger A, Merkenschlager A, et al. Is there a predictive value of EEG and MRI after a first afebrile seizure in children?. Klin Padiatr. 2015;227(2):84-8.
[18]Mohamed Y, Alias NN, Shuaib IL, Tharakan J, Abdullah J, Munawir AH, et al. Referral of epileptic patients in North East Coast of West Malaysia an area with poor MRI coverage: an analysis. Southeast Asian J Trop Med Public Health. 2006;37(6):1199-208.
[19]Byars AW, deGrauw TJ, Johnson CS, Fastenau PS, Perkins SM, Egelhoff JC, et al. The Association of MRI findings and neuropsychological functioning after the first recognized seizure. Epilepsia. 2007;48(6):1067-74.
[20]Dehghani Firuzabadi M, Mohammadifarrd M, Sharifzadeh G, Mohammadifard M. MRI findings and clinical symptoms of patients with epilepsy referring to Valli-e-asr Hospital between 2009 and 2010. J Birjand Univ Med Sci. 2013;19(4):422-9. [Persian]
[21]Grévent D, Calmon R, Brunelle F, Boddaert N. [Brain imaging in seizures]. Rev Prat. 2012;62(10):1391-4. [French]
[22]Sharieff GQ, Hendry PL. Afebrile pediatric seizures. Emerg Med Clin North Am. 2011;29(1):95-108.
[23]Hashemi AH, Homam M, Naghib S. Unenhanced brain CT findings in afebrile patients over five years age with first episode of seizure. Iran J Radiol. 2008;5(Suppl 1):32-3. [Persian]
[24]Nasehi MM, Shamsabadi F, Ghofrani M. Paraclinical findings and treatment response of children with refractory epilepsy in Mofid Children's Hospital in 2007-2008. J Mazandaran Univ Med Sci. 2009;20(75):24-9. [Persian]
[25]Sue H, Nakayama K. [Clinical examination on localization-related epilepsies with elementary visual seizures--clinical, electroencephalographic and imaging diagnostic studies]. Seishin Shinkeigaku Zasshi. 1997;99(9):688-705. [Japanese]
[26]Sanmaneechai O, Danchaivijitr N, Likasitwattanakul S. Predictors of abnormal neuroimaging of the brain in children with epilepsy aged 1 month to 2 years: useful clues in a resource-limited setting. J Child Neurol. 2015;30(11):1532-6.